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Adjust an observed odds ratio for a normally distributed confounder

Usage

adjust_or(
  effect_observed,
  exposure_confounder_effect,
  confounder_outcome_effect,
  verbose = getOption("tipr.verbose", TRUE),
  or_correction = FALSE
)

adjust_or_with_continuous(
  effect_observed,
  exposure_confounder_effect,
  confounder_outcome_effect,
  verbose = getOption("tipr.verbose", TRUE),
  or_correction = FALSE
)

Arguments

effect_observed

Numeric positive value. Observed exposure - outcome odds ratio. This can be the point estimate, lower confidence bound, or upper confidence bound.

exposure_confounder_effect

Numeric. Estimated difference in scaled means between the unmeasured confounder in the exposed population and unexposed population

confounder_outcome_effect

Numeric. Estimated relationship between the unmeasured confounder and the outcome.

verbose

Logical. Indicates whether to print informative message. Default: TRUE

or_correction

Logical. Indicates whether to use a correction factor. The methods used for this function are based on risk ratios. For rare outcomes, an odds ratio approximates a risk ratio. For common outcomes, a correction factor is needed. If you have a common outcome (>15%), set this to TRUE. Default: FALSE.

Value

Data frame.

Examples

adjust_or(1.2, 0.9, 1.3)
#>  The observed effect (OR: 1.2) is updated to OR: 0.95 by a confounder with the
#>   following specifications:
#>  estimated difference in scaled means: 0.9
#>  estimated relationship (OR) between the unmeasured confounder and the
#>   outcome: 1.3
#> # A tibble: 1 × 4
#>   or_adjusted or_observed exposure_confounder_effect confounder_outcome_effect
#>         <dbl>       <dbl>                      <dbl>                     <dbl>
#> 1       0.948         1.2                        0.9                       1.3